- Contact Person : Ms. Lee Summer
- Company Name : Zibo Titan International Trade Co., Ltd.
- Tel : 86-533-6121101
- Fax : 86-533-6121101
- Address : Shandong,Zibo,Tower B, Guomao Building, Zhangdian Branch,
- Country/Region : China
- Zip : 255000
Hydroxypropyl Methyl Cellulose Phthalate HPMCP HP55
Brief Introduction
The enteric coating material gentle release reinforcing material, enteric-coated capsules and microencapsulation matrix adhesives, implants, gradient release system, taste masking agents, microspheres, oral membrane , such as preparation of solid dispersions, the release rate and the PH value of the related.
Technical specification:
Comply with USP and EP.
Item | Grade | |
HP55 | HP55S | |
Methoxy(WT%) | 18.0-22.0 | 18.0-22.0 |
Hydroxypropoxy(WT%) | 5.0-9.0 | 5.0-9.0 |
Phthaloyl group(WT%) | 27.0-35.0 | 27.0-35.0 |
Viscosity(mPa.s)(10%solu.,20±0.1°C) | 32-48 | 136-204 |
Loss on drying(%) | ≤5.0 | ≤5.0 |
Residue on ignition(%) | ≤0.20 | ≤0.20 |
Chloride(%) | ≤0.07 | ≤0.07 |
Heavy metals(ppm) | ≤10 | ≤10 |
Preparation of coating solution
1)Concentration of coating solution
Item | Tablet | Granule |
HP55 | 6-10% | 5-7% |
HP55S | 5-8% | 4-6% |
2)Organic solvents for HP
Acetone: Water =9:1 Methylene chloride: Ethanol =1:1 Acetone: Ethanol = 1:1 Ethanol: Water = 8:2 (Solution temperature above 25°C) Methylene chloride: Ethanol: Water = 5:4:1
3)Dissolving method
Added to the container a certain amount of solvent, under stirring, slowly add HPMCP stir until fully formed viscosity.
4)HPMCP usage is generally 6-10% the amount of core chip.
Package&Storage
20Kg fiber drum with PE inner liner
20 feet container can load 7.2MT with palletized and 8MT without palletized; Packing size: H500mm x D380mm
3 years under cool, dry condition in original packing away from heat sources. It is recomended to use the product in rotation on a first-in-first-out basis.
Hydroxypropyl Methyl Cellulose Phthalate HPMCP HP55